Doheny Image Reading and Research Lab (DIRRL)

Research Fellows and Publications

Ahmed Roshdy Zeyada AlAgorie, MD

Research Fellow

(Joined Doheny 7/2018)

Amirhossein Hariri, MD

Research Fellow/Investigator

(Joined Doheny 6/2011)

Ayesha Karamat, MPH, MBBS

Research Grader/Research Fellow

(Joined Doheny 7/2016)

Giulia Corradetti, MD

Research Fellow

(Joined Doheny 1/2019)

Iksoo Byon, MD

Research Fellow

(Joined Doheny 8/2018)

Jyotsna Maram, OD, PhD

Research Fellow/Research Associate

(Re-Joined Doheny 10/2016)

Liran Tiosano, MD

Research Fellow

(Joined Doheny 1/2019)

Mengyuan Fang, MD, PhD

Research Fellow

(Joined Doheny 12/2017)

Mengyuan Fang, MD, PhD

Research Fellow

(Joined Doheny 12/2017)

Muneeswar Gupta Nittala, MPhil

Research Fellow/Senior Research Associate

(Joined Doheny 6/2010)

  • Nittala MG, Hariri A, Wong WT, et al. Image Scaling Difference Between a Confocal Scanning Laser Ophthalmoscope and a Flash Fundus Camera. Ophthalmic Surgery, Lasers Imaging Retin 2015;46:872–879.
  • Nittala MG, Velaga SB, Hu Z, Sadda SR. Relationship Between Dry Retinal Volume and Visual Acuity in Diabetic Macular Edema. Ophthalmic Surgery, Lasers Imaging Retin 2018;49:510–515.
  • Nittala MG, Song YE, Sardell R, et al. AMISH EYE STUDY Baseline Spectral Domain Optical Coherence Tomography Characteristics of Age-Related Macular Degeneration. Retina 2018;0:1–11.
  • Nittala MG, Laxmi G, Raman R, et al. Spectral-domain OCT and microperimeter characterization of morphological and functional changes in X-linked retinoschisis. Ophthalmic Surg Lasers Imaging 2009;40:71–4.
  • Nittala MG, Konduru R, Ruiz-Garcia H, Sadda SR. Effect of OCT volume scan density on thickness measurements in diabetic macular edema. Eye 2011;25:1347–1355.
  • Nittala MG, Keane PA, Zhang K, Sadda SR. Risk Factors for Proliferative Diabetic Retinopathy in a Latino American Population. Retina. 2014 Aug;34(8):1594-9.
  • Nittala MG, Gella L, Raman R, Sharma T. Measuring retinal sensitivity with the microperimeter in patients with Retina 2012;32:1302–1309.
  • Nittala MG, Ruiz-Garcia H, Sadda SVR. Accuracy and reproducibility of automated drusen segmentation in eyes with non-neovascular age-related macular degeneration. Investig Ophthalmol Vis Sci 2012;53:8319–8324.
  • Sharma T, Gella L, Nittala M, et al. Morphological and functional changes in spectral domain optical coherence tomography and microperimetry in macular microhole variants: Spectral domain optical coherence tomography and microperimetry correlation. Indian J Ophthalmol 2012;60:53.
  • Kothari AR, Raman RP, Sharma T, Gupta M, Laxmi G. Is there a correlation between structural alterations and retinal sensitivity in morphological patterns of diabetic macular edema? Indian J Ophthalmol 2013;61:230–232.
  • Qu J, Velaga SB, Hariri AH1, Nittala MG, Sadda S. Classification and Quantitative Analysis of Geographic Atrophy Junctional Zone Using Spectral Domain Optical Coherence Tomography. Retina. 2018 Aug;38(8):1456-1463.
  • Hirano T, Kakihara S, Toriyama Y, Nittala MG, Murata T, Sadda S. Wide-field en face swept-source optical coherence tomography angiography using extended field imaging in diabetic retinopathy. Br J Ophthalmol. 2017 Nov 29.
  • Sears CM, Nittala MG, Jayadev C, et al. Comparison of subjective assessment and precise quantitative assessment of lesion distribution in diabetic retinopathy. JAMA Ophthalmol 2018;136:365–371.
  • Ebraheem A, Uji A, Saleh Abdelfattah N, MG Nittala, Sadda SR, Le PV. Relationship between the Presence of a Cilioretinal Artery and Subretinal Fluid in Neovascular Age-Related Macular Degeneration. Ophthalmol Retin 2018;2:469–474.
  • Wang K, Jayadev C, Nittala MG, et al. Automated detection of diabetic retinopathy lesions on ultrawidefield pseudocolour images. Acta Ophthalmol 2018;96:e168–e173.
  • Mittal A, Velaga SB, Falavarjani KG, MG Nittala, Sadda SR . Choroidal thickness in non-ocular Behçet’s disease – A spectral-domain OCT study. J Curr Ophthalmol 2017;29:210–213.
  • Strauss RW, Muñoz B, Ho A, Jha A, Michaelides M, Mohand-Said S, Cideciyan AV, Birch D, Hariri AH, Nittala MG, Sadda S, Scholl HPN; ProgStar Study Group. Incidence of atrophic lesions in Stargardt disease in the progression of atrophy secondary to Stargardt disease (ProgStar) study report No. 5. JAMA Ophthalmol 2017;135:687–695.
  • Lei J, Balasubramanian S, Abdelfattah NS, Nittala MG, Sadda SR. Proposal of a simple optical coherence tomography-based scoring system for progression of age-related macular degeneration. Graefe’s Arch Clin Exp Ophthalmol 2017;255:1551–1558.
  • Balasubramanian S, Uji A, Lei J, Velaga S, Nittala M, Sadda S. Interdevice comparison of retinal sensitivity assessments in a healthy population: The CenterVue MAIA and the Nidek MP-3 microperimeters. Br J Ophthalmol 2017:1–5.
  • Pan X, Marion K, Maram J, Zhang ZY, Francis BA, Nittala MG, Sadda SR, Chopra V. Reproducibility of Anterior Segment Angle Metrics Measurements Derived From Cirrus Spectral Domain Optical Coherence Tomography. J Glaucoma 2015;24:e47–e51.
  • Bhaskaranand, Malavika & Cuadros, Jorge & Ramachandra, Chaithanya & Bhat, Sandeep & Nittala, Muneeswar & R. Sadda, Srinivas & Solanki, Kaushal. (2015). EyeArt + EyePACS: Automated Retinal Image Analysis For Diabetic Retinopathy Screening in a Telemedicine System. 105-112. 10.17077/omia.1033.
  • Srinivas S, Nittala MG, Hariri A, et al. Quantification of Intraretinal Hard Exudates in Eyes with Diabetic Retinopathy by Optical Coherence Tomography. Retina 2018;38:231–236.
  • Hariri A, Diniz B, Fou L V, Lam LA, Nittala MG, Sadda SR. Quantitative OCT Subanalysis of Eyes With Choroidal Neovascularization Switched From Multiple Injections of Bevacizumab or Ranibizumab to Intravitreal Aflibercept. Ophthalmic Surgery, Lasers Imaging Retin 2015;46:195–200.
  • Hariri AH, Tepelus TC, Akil H, Nittala MG, Sadda SR. Retinal Sensitivity at the Junctional Zone of Eyes with Geographic Atrophy Due to Age-Related Macular Degeneration. Am J Ophthalmol 2016;168:122–128.
  • Velaga S, Nittala M, Parinitha B, et al. Correlation between retinal sensitivity and cystoid space characteristics in diabetic macular edema. Indian J Ophthalmol 2016;64:452.
  • Tufail A, Rudisill C, Egan C, Kapetanakis VV, Salas-Vega S, Owen CG, Lee A, Louw V, Anderson J, Liew G3, Bolter L, Srinivas S, Nittala M, Sadda S, Taylor P, Rudnicka AR. Automated Diabetic Retinopathy Image Assessment Software: Diagnostic Accuracy and Cost-Effectiveness Compared with Human Graders. Ophthalmology 2017;124:343–351.
  • Ratra V, Ratra D, Gupta M, Vaitheeswaran K. Comparison between Humphrey Field Analyzer and Micro Perimeter 1 in normal and glaucoma subjects. Oman J Ophthalmol 2012;5:97.
  • Srinivas S, Dastiridou A, Durbin MK, Nittala MG, Huang AA, Tan JC, Francis BA, Sadda SR, Chopra al. Pilot Study of Lamina Cribrosa Intensity Measurements in Glaucoma Using Swept-Source Optical Coherence Tomography. J Glaucoma 2016;00:1.
  • Raman R, Gella L, Nittala M. Retinal sensitivity in healthy Indians using microperimeter. Indian J Ophthalmol 2014;62:284. Available at:
  • Srinivas S, Tan O, Wu S, Nittala MG, Huang D, Varma R, Sadda SR. Measurement of retinal blood flow in normal Chinese-American subjects by doppler fourier-domain optical coherence tomography. Investig Ophthalmol Vis Sci 2015;56:1569–1574.
  • Gupta A, Laxmi G, Nittala MG, Raman R. Structural and functional correlates in color vision deficiency. Eye 2011;25:909–917.
  • Yehoshua Z, Gregori G, Sadda SVR, Penha FM, Goldhardt R, Nittala MG, Konduru RK, Feuer WJ, Gupta P, Li Y, Rosenfeld PJ. Comparison of drusen area detected by spectral domain optical coherence tomography and color fundus imaging. Investig Ophthalmol Vis Sci 2013;54:2429–2434.
  • Charafeddin W, Nittala MG, Oregon A, Sadda SR. Relationship Between Subretinal Hyperreflective Material Reflectivity and Volume in Patients With Neovascular Age-Related Macular Degeneration Following Anti-Vascular Endothelial Growth Factor Treatment. Ophthalmic Surgery, Lasers Imaging Retin 2015;46:523–530.
  • Raman R, Nittala MG, Gella L, et al. Retinal sensitivity over hard exudates in diabetic retinopathy. J Ophthalmic Vis Res 2015;10:160–164.
  • Verma A, Raman R, Vaitheeswaran K, Pal SS, Laxmi G, Gupta M, Shekar SC, Sharma T. et al. Does neuronal damage precede vascular damage in subjects with type 2 diabetes mellitus and having no clinical diabetic retinopathy? Ophthalmic Res 2012;47:202–207.
  • Konduru RK, Tan O, Nittala MG, et al. Reproducibility of Retinal Blood Flow Measurements Derived From Semi-Automated Doppler OCT Analysis. Ophthalmic Surgery, Lasers, and Imaging 2012;43:25–31.
  • Sardell RJ, Nittala MG, Adams LD, et al. Heritability of Choroidal Thickness in the Amish. Ophthalmology 2016;123:2537–2544.
  • Hariri A, Nittala MG, Sadda SR. Outer retinal tubulation as a predictor of the enlargement amount of geographic atrophy in age-related macular degeneration. Ophthalmology 2015;122:407–413.
  • Bhaskaranand M, Ramachandra C, Bhat S, Cuadros J, Nittala MG, Sadda S, Solanki K. Automated Diabetic Retinopathy Screening and Monitoring Using Retinal Fundus Image Analysis. J Diabetes Sci Technol 2016;10:254–261.
  • Hariri A, Lee SY, Ruiz-Garcia H, Nittala MG, Heussen FM, Sadda SR. Effect of Angle of Incidence on Macular Thickness and Volume Measurements Obtained by Spectral-Domain Optical Coherence Tomography. Investig Opthalmology Vis Sci 2012;53:5287.
  • Hariri AH, Nittala MG, Sadda SR. Quantitative Characteristics of Spectral-Domain Optical Coherence Tomography in Corresponding Areas of Increased Autofluorescence at the Margin of Geographic Atrophy in Patients With Age-Related Macular Degeneration. Ophthalmic Surgery, Lasers Imaging Retin 2016;47:523–527.
  • Pappuru RR, Ouyang Y, Nittala MG, et al. Relationship between outer retinal thickness substructures and visual acuity in eyes with dry age-related macular degeneration. Investig Ophthalmol Vis Sci 2011;52:6743–6748.
  • Verma a, Rani PK, Raman R, Pal SS, Laxmi G, Gupta M, Sahu C, Vaitheeswaran K, Sharma T.. Is neuronal dysfunction an early sign of diabetic retinopathy? Microperimetry and spectral domain optical coherence tomography (SD-OCT) study in individuals with diabetes, but no diabetic retinopathy. Eye (Lond) 2009;23:1824–30.

Automated characterization of pigment epithelial detachment by optical coherence tomography

Lee SY, Stetson PF, Ruiz-Garcia H, Heussen FM, Sadda SR. Investigative Ophthalmology & Visual Science. 2012;53(1):164-70.

Clinical significance of B-scan averaging with SD-OCT

Pappuru RR, Briceno C, Ouyang Y, Walsh AC, Sadda SR. Ophthalmic Surgery Lasers & Imaging. 2012;43(1):63-8.

Spatial distribution of posterior pole choroidal thickness by spectral domain optical coherence tomography

Ouyang Y, Heussen FM, Mokwa N, Walsh AC, Durbin MK, Keane PA, Sanchez PJ, Ruiz-Garcia H, Sadda SR. Investigative Ophthalmology & Visual Science. 2012:53(9):6682-6.

Relationship between outer retinal thickness substructures and visual acuity in eyes with dry age-related macular degeneration

Pappuru RR, Ouyang Y, Nittala MG, Hemmati HD, Keane PA, Walsh AC, Sadda SR. Investigative Ophthalmology & Visual Science. 2011;52(9):6743-8.

Intraretinal segmentation on fourier domain optical coherence tomography

Huang J, Liu X, Wu Z, Cao D, Sadda S. Annals of the Academy of Medicine Singapore. 2010;39(7):518-7.

Imaging chorioretinal vascular disease

Keane PA, Sadda SR. Eye. 2010;24(3):422-7.